Multiscale Modeling of
Living Matter Group
Permanent Members
PhD students and Post-docs
image by Hua Wong
Recent Publications
2013
Multiscale
Analysis of Biological Systems.
Lesne A.
Acta Biotheor.
2013 Jan 18.
2012
Pulling
chromatin apart: Unstacking or Unwrapping?
Victor JM, Zlatanova J, Barbi M, Mozziconacci J.
BMC Biophys. 2012
Nov 27;5:21.
DNA
topology in chromosomes: a quantitative survey and its
physiological implications.
Barbi M, Mozziconacci J, Wong H, Victor JM.
J Math
Biol. 2012 Nov 20.
Normalization
of a chromosomal contact map.
Cournac A, Marie-Nelly H, Marbouty M, Koszul R, Mozziconacci
J.
BMC Genomics. 2012
Aug 30;13:436
Nucleosome
positioning and nucleosome stacking: two faces of the same coin.
Riposo J, Mozziconacci J.
Mol Biosyst.
2012 Apr;8(4):1172-8.
CDS:
a fold-change based statistical test for concomitant
identification of distinctness and similarity in gene expression
analysis.
Tchitchek N, Dzib JF, Targat B, Noth S, Benecke A, Lesne
A.
Genomics
Proteomics Bioinformatics. 2012 Jun;10(3):127-35.
Building
blocks of self-sustained activity in a simple deterministic
model of excitable neural networks.
Garcia GC, Lesne A, Hütt MT, Hilgetag
CC.
Front
Comput Neurosci. 2012;6:50
The
condensed chromatin fiber: an allosteric chemo-mechanical
machine for signal transduction and genome processing.
Lesne A, Bécavin C, Victor JM.
Phys Biol. 2012
Feb;9(1):013001
2011
Co-transcriptional
architecture in a Y loop in Drosophila melanogaster.
Redhouse JL, Mozziconacci J, White RA.
Chromosoma. 2011
Aug;120(4):399-407
Effective
interaction between charged nanoparticles and DNA.
Paillusson F, Dahirel V, Jardat M, Victor JM,
Barbi M.
Phys Chem Chem Phys. 2011 Jul 21;13(27):12603-13
Linker
histones incorporation maintains chromatin fiber plasticity.
Recouvreux P, Lavelle C, Barbi M, Conde E Silva N,
Le Cam E, Victor JM, Viovy JL.
Biophys J.
2011 Jun 8;100(11):2726-35
Delay
independence of mutual-information rate of two symbolic
sequences.
Blanc JL, Pezard L, Lesne A.
Phys Rev E Stat Nonlin Soft
Matter Phys. 2011 Sep
Genetic
susceptibility to a complex disease: the key role of functional
redundancy.
Debret G, Jung C, Hugot JP, Pascoe L, Victor
JM, Lesne A.
Hist Philos Life Sci.
2011;33(4):497-514.
2010
Intra-
and inter-chromosomal interactions correlate with CTCF binding
genome wide.
Botta M, Haider S, Leung IX, Lio P, Mozziconacci
J.
Mol Syst Biol.
2010 Nov 2;6:426
Chromatin fiber dynamics
under tension and torsion.
Lavelle C, Victor JM, Zlatanova J.
Int J Mol Sci. 2010 Apr 12;11(4):1557-79.PMID: 20480035
Transcription within
condensed chromatin: Steric hindrance facilitates elongation.
Becavin C, Barbi M, Victor JM, Lesne A.
Biophys J. 2010 Mar 3;98(5):824-33.PMID: 20197036
2009
Molecular crowding affects
diffusion and binding of nuclear proteins in heterochromatin and
reveals the fractal organization of chromatin.
Bancaud A, Huet S, Daigle N, Mozziconacci J, Beaudouin J, Ellenberg
J.
EMBO J. 2009 Dec 16;28(24):3785-98. Epub .PMID: 19927119
A molecular model of
chromatin organisation and transcription: how a multi-RNA
polymerase II machine transcribes and remodels the beta-globin
locus during development.
Wong H, Winn PJ, Mozziconacci J.
Bioessays. 2009 Dec;31(12):1357-66.PMID: 19877003
How are nucleosomes
disrupted during transcription elongation?
Zlatanova J, Victor JM.
HFSP J. 2009 Dec;3(6):373-8. Epub 2009 Nov 12.PMID: 20514129
Right-handed nucleosome:
myth or reality?
Lavelle C, Recouvreux P, Wong H, Bancaud A, Viovy JL, Prunell A,
Victor JM.
Cell. 2009 Dec 24;139(7):1216-7; author reply 1217-8. No abstract
available. PMID: 20064364
Nonspecific DNA-protein
interaction: why proteins can diffuse along DNA.
Dahirel V, Paillusson F, Jardat M, Barbi M, Victor JM.
Phys Rev Lett. 2009 Jun 5;102(22):228101. Epub 2009 Jun 2.PMID:
19658903
The nucleosome family:
dynamic and growing.
Zlatanova J, Bishop TC, Victor JM, Jackson V, van Holde K.
Structure. 2009 Feb 13;17(2):160-71. Review.PMID: 19217387
Interplay between Topology
and Dynamics in Excitation Patterns on Hierarchical Graphs.
Hutt MT, Lesne A.
Front Neuroinformatics. 2009;3:28. Epub 2009 Sep 15.PMID: 19826610
Systems biology: the
multiscale organization of living systems
Lesne A.
Med Sci (Paris). 2009 Jun-Jul;25(6-7):585-7. Review. French. PMID:
19602355
Entropy estimation of very
short symbolic sequences.
Lesne A, Blanc JL, Pezard L.
Phys Rev E Stat Nonlin Soft Matter Phys. 2009 Apr;79(4 Pt 2):046208.
Epub 2009 Apr 7.PMID: 19518313
AER1, a major gene
conferring resistance to Aphanomyces euteiches in Medicago
truncatula.
Pilet-Nayel ML, Prosperi JM, Hamon C, Lesne A, Lecointe R, Le Goff
I, Herve M, Deniot G, Delalande M, Huguet T, Jacquet C, Baranger A.
Phytopathology. 2009 Feb;99(2):203-8.PMID: 19159312
Sequence-driven telomeric
chromatin structure.
Revaud D, Mozziconacci J, Sabatier L, Desmaze C, Lavelle C.
Cell Cycle. 2009 Apr 1;8(7):1099-100. Epub 2009 Apr 4.PMID: 19270515
2008
Tubulin dimers oligomerize
before their incorporation into microtubules.
Mozziconacci J, Sandblad L, Wachsmuth M, Brunner D, Karsenti E.
PLoS One. 2008;3(11):e3821. Epub 2008 Nov 27.PMID: 19043587
Behavioral sequence
analysis reveals a novel role for beta2* nicotinic receptors in
exploration.
Maubourguet N, Lesne A, Changeux JP, Maskos U, Faure P.
PLoS Comput Biol. 2008 Nov;4(11):e1000229. Epub 2008 Nov 21.PMID:
19023420
Robustness: confronting
lessons from physics and biology.
Lesne A.
Biol Rev Camb Philos Soc. 2008 Nov;83(4):509-32. Epub 2008 Sep 24.
Review.PMID: 18823391
Feature context-dependency
and complexity-reduction in probability landscapes for
integrative genomics.
Lesne A, Benecke A.
Theor Biol Med Model. 2008 Sep 10;5:21.PMID: 18783599
Cellular automata approach
of transmembrane ionic currents.
Pezard L, Lesne A.
J Integr Neurosci. 2008 Jun;7(2):271-86.PMID: 18763724
2007
An all-atom model of the
chromatin fiber containing linker histones reveals a versatile
structure tuned by the nucleosomal repeat length.
Wong H, Victor JM, Mozziconacci J.
PLoS One. 2007 Sep 12;2(9):e877.PMID: 17849006
Nucleosome chiral transition
under positive torsional stress in single chromatin fibers.
Bancaud A, Wagner G, Conde E Silva N, Lavelle C, Wong H,
Mozziconacci J, Barbi M, Sivolob A, Le Cam E, Mouawad L, Viovy JL,
Victor JM, Prunell A.
Mol Cell. 2007 Jul 6;27(1):135-47.PMID: 17612496
Dynamics of emotional
expression in autobiographic speech of patients with anorexia
nervosa.
Doba K, Pezard L, Lesne A, Vignau J, Christophe V, Nandrino JL.
Psychol Rep. 2007 Aug;101(1):237-49.PMID: 17958131 [
2006
Structural plasticity of
single chromatin fibers revealed by torsional manipulation.
Bancaud A, Conde e Silva N, Barbi M, Wagner G, Allemand JF,
Mozziconacci J, Lavelle C, Croquette V, Victor JM, Prunell A, Viovy
JL.
Nat Struct Mol Biol. 2006 May;13(5):444-50. Epub 2006 Apr 16.PMID:
16622406
A physical model for the
condensation and decondensation of eukaryotic chromosomes.
Mozziconacci J, Lavelle C, Barbi M, Lesne A, Victor JM.
FEBS Lett. 2006 Jan 23;580(2):368-72. Epub 2005 Dec 27.PMID:
16387302
Autobiographical memory
deficit in anorexia nervosa: emotion regulation and effect of
duration of illness.
Nandrino JL, Doba K, Lesne A, Christophe V, Pezard L.
J Psychosom Res. 2006 Oct;61(4):537-43.PMID: 17011363
SAGA interacting factors
confine sub-diffusion of transcribed genes to the nuclear
envelope.
Cabal GG, Genovesio A, Rodriguez-Navarro S, Zimmer C, Gadal O, Lesne
A, Buc H, Feuerbach-Fournier F, Olivo-Marin JC, Hurt EC, Nehrbass U.
Nature. 2006 Jun 8;441(7094):770-3.PMID: 16760982
Chromatin fiber functional
organization: some plausible models.
Lesne A, Victor JM.
Eur Phys J E Soft Matter. 2006 Mar;19(3):279-90. Epub 2006 Feb
23.PMID: 16501875
The chromatin regulatory
code: beyond a histone code.
Lesne A.
Eur Phys J E Soft Matter. 2006 Mar;19(3):375-7. Epub 2006 Feb
10.PMID: 16470338
